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Ions in neutropenic patients stem from hematological patients and have to be validated in the ICU setting.Competing interests The authors declare that they have no competing interests. Authors' contributions LZ and EA carried out a review of the literature and wrote the manuscript. Both authors read and approved the final manuscript. Received: 8 April 2014 Accepted: 9 September 2014 Published: 28
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With decreased porin production after the use of carbapenems [62]. Enterobacteriaceae that produce Klebsiella pneumonia- To date, posaconazole is only available in oral suspension. A study evaluating the pharmacokinetics and adverse effects of an intravenous formulation of posaconazole is currently being completed (ClinicalTrials.gov. Pharmacokinetics, safety, and tolerability of intravenous posac
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Hose with associated bacteremia) with linezolid often used as a first-line treatment. Early reports of linezolid resistant enterococci occurred predominantly in immunocompromised hosts who resided in an ICU [68].New antifungal drugsPolyclonal intravenous immunoglobulins have been suggested to be beneficial during sepsis by modulating the immune response and neutralizing bacterial endo and exotoxin
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Hose with associated bacteremia) with linezolid often used as a first-line treatment. Early reports of linezolid resistant enterococci occurred predominantly in immunocompromised hosts who resided in an ICU [68].New antifungal drugsPolyclonal intravenous immunoglobulins have been suggested to be beneficial during sepsis by modulating the immune response and neutralizing bacterial endo and exotoxin
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Nic sepsis that is unresponsive to conventional antimicrobial therapy. However, therapeutic administration of granulocyte transfusions in the neutropenic host with severe infection has no proven benefit. A cochrane database systematic review concludes that there is inconclusive evidence to support or refute the use of granulocyte transfusions [58]. More recently, in 30 severely ill neutropenic pat
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Nic sepsis that is unresponsive to conventional antimicrobial therapy. However, therapeutic administration of granulocyte transfusions in the neutropenic host with severe infection has no proven benefit. A cochrane database systematic review concludes that there is inconclusive evidence to support or refute the use of granulocyte transfusions [58]. More recently, in 30 severely ill neutropenic pat
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The small or large intestine is indicative of pneumatosis intestinalis. This situation refers to a necrotizing enterocolitis and can be considered as an indication for urgent surgery. Conservative management is recommended initially when these criteria are absent [50]. Badgwell et al. suggested better outcomes if it was possible to delay surgery until recovery from neutropenia [51]. General suppor
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And H4 acetylation patterns across the DES locus and surrounding 500 kb region, we next sought to obtain a more detailed map of epigenetic status specifically across the DES LCR, as this constitutes a crucial regulatory element. Chromatin used for the microarray analysis was analysed by Q-PCR to assess enrichment for selected regions within DES and the DES LCR.The ENCODE region ENr331 which spans