R pM1o (,2400 bp), and the position of Dpn1resistent replicating genomes is denoted by an arrow at days 3? p.t. Dpn1- and EcoRI-sensitive input DNAs are noted at the day 0 time point. doi:10.1371/journal.pone.0010606.gdetectably to purified free C subunit [57]. Given this information, our data suggest JCV tAg binds the scaffold subunit (A) of the AC core of PP2A in rat and mouse fibroblasts and no