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Of the ompATb mutant CK69 was observed in either lungs or spleens (Fig. S6). Taken together, our in vivo experiments with two ompATb mutants show that neither OmpATb nor Rv0900 and Rv0901 are required for full virulence of M. tuberculosis in a mouse infection model.NIH-PA Author Manuscript NIH-PA Author Manuscript NIH-PA Author ManuscriptDISCUSSIONOmpATb lacks porin activity in vivo In this study