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Ification of hematein as a novel inhibitor of protein kinase CK2 from a natural product libraryMing-Szu Hung1,2,3, Zhidong Xu1, Yu-Ching Lin2,3, Jian-Hua Mao4, ChengTa Yang2,5, Pey-Jium Chang3, David M Jablons*1 and Liang You*Address: 1Thoracic Oncology Laboratory, Department of Surgery, Comprehensive Cancer Center, University of California, San Francisco, CA 94115, USA, 2Division of Pulmonary and
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D the antinociceptive effects of viral vectors, asBased on the behavioral results, we examined the expression of the endomorphins and serine histogranin in the dorsal horn of the spinal cord seven weeks after viral vector injection. Sections were labeled for endomorphins or SHG immunoreactivity. Immunoreactive positive cells for SHG (A) and endomorphins (B) were seen in the dorsal horn at the 7th
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Lyna, M., Simpson, C.G., Syed, N.H., Lewandowska, d., Marquez, Y., Kusenda, B., Marshall, J., Fuller, J., Cardle, L., McNicol, J., dinh, H.q., Barta, A., and Brown, J.W. (2012). Alternative splicing and nonsense-mediated decay modulate expression of important regulatory genes in Arabidopsis. Nucl. Acids Res. 40: 2454-2469. Kamauchi, S., Nakatani, H., Nakano, C., and urade, R. (2005). Gene expressi
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Express vIF2a or K3L under the control of the galactose regulated GAL-CYC1 promoter. Yeast transformants were streaked on synthetic complete medium containing galactose (SC-Gal) and incubated at different temperatures. At permissive temperatures (27 and 30 ) all transformants grew well (Figure 3). However, when incubated at restrictive temperatures (33 and 36 ), only wild type eIF2a was able to
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Nces between GFP and single-vector injected groups were observed as well with modest, but significant differences at some time points (overall F(df 4,9) =10.1).Effect of delayed injection of viral vectors on pain behaviorTo mimic clinical scenarios, the effect of time of delivery of therapeutic agents in chronically injured animals has to be considered. Therefore we evaluated the analgesic effect
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And Smeekens, S. (2008). The sucrose regulated transcription factor bZIP11 affects amino acid metabolism by regulating the expression of ASPARAGINE SYNTHETASE1 and PROLINE DEHYDROGENASE2. Plant J. 53: 935-949. Hart, P.E., and Wolniak, S.M. (1999). Molecular cloning of a centrin homolog from Marsilea vestita and evidence for its translational control during spermiogenesis. Biochem. Cell Biol. 77: 1