N activator streptokinase might contribute to contact system activation by S. pyogenes. Here, we report that the human contact system is activated by the action of streptokinase. The role of secreted and surfacebound streptokinase in this process was investigated by comparing an M49 S. pyogenes wild-type strain with its isogenic ska mutant, which is unable to trigger plasmin activity in human plas
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S and signature sequences: evolutionary relationships within prokaryotes and between prokaryotes and eukaryotes. Antonie Leeuwenhoek 72:49?1. 100. Gupta, R. S. 1998. Life's third domain (Archaea): an established fact or an endangered paradigm? A new proposal for classification of organisms based on protein sequences and cell structure. Theor. Popul. Biol. 54:91?104. 101. Gupta, R. S. 1998. What ar
More susceptible to UTIs than are healthy patients because of the greater adherence of type 1 fimbriated E. coli to bladder cells (57). The LGI network of Candida Als and Epa adhesins N-Als1p has been shown to interact with fucose-containing glycans that are present in blood group antigens and preferentially with antigen Htype 2 (22). Therefore, we performed glycan array screening to also determin
Ansfected cells from untransfected cells by FACS analyses.MCF-p=0.p=0.0001 p=0.0001 p=0.Figure 4 Histone signature at the MAGE-A1 promoter as examined by chromatin immunoprecipitation. DNA was derived from unstimulated (basal) MCF-7 cells, 5-aza-CdR- and/or TSA-stimulated MCF-7 cells and MCF-7 cells transfected with the expression plasmid encoding for BORIS. DNA-bound histones were immunoprecipita
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Ation of noncovalent complexes of recombinant human monoclonal antibody and antigen using cation exchange, size exclusion chromatography, and BIAcore. Analyt Biochem. 2001;299(2):119?9. Nesbitt A, Fossati G, Bergin M, Stephens P, Stephens S, Foulkes R, et al. Mechanism of action of certolizumab pegol (CDP870): in vitro comparison with other anti-tumor necrosis factor alpha agents. Inflamm Bowel Di